Award
National Heart, Lung, and Blood Institute 5R01HL163960-05
Network Medicine and Systems Pharmacology to Advance Precision Medicine in Combined Pulmonary Hypertension
Recipient
Vanderbilt University Medical Center
Award Amount
$592,928.00
Ceiling
$592,928.00
Awarded
May 18, 2026
Identifier
5R01HL163960-05
The award supports research to advance precision medicine in combined pulmonary hypertension by using network medicine and systems pharmacology to identify biomarkers and therapeutic targets, leveraging patient-specific molecular profiles.
Description
This project aims to develop patient-specific network models to identify biomarkers and therapeutic targets for pulmonary hypertension related to left heart failure. It includes transcriptome profiling, biomarker validation, and N-of-1 clinical trials, funded by the National Heart Lung and Blood Institute (NHLBI) and involves collaboration with Vanderbilt University Medical Center.