Award
NIH Reporter #10912096
Impact of dysbiotic and symbiotic catabolism of luminal amino acids on intestinal epithelial barrier function and inflammation
Recipient
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Award Amount
$375,080.00
Ceiling
$375,080.00
Awarded
September 20, 2023
Identifier
10912096
Research project funded by NIDDK to study the role of microbiota-produced polyamines in intestinal barrier function and inflammation, using advanced techniques for potential gastrointestinal disease therapies.
Description
The project focuses on investigating how microbiota-produced polyamines regulate intestinal epithelial barrier function and inflammation, with potential therapeutic implications for gastrointestinal diseases. The project employs innovative techniques including knockout mice and pathogen-specific antibacterial agents.