Award
National Heart, Lung, and Blood Institute 1K99HL183664-01A1
Targeting Angiocrine Signaling in Vascular Repair and Ischemic Stroke Recovery
Recipient
Kulandaisamy Arulsamy
Award Amount
$139,822.00
Ceiling
$139,822.00
Awarded
July 22, 2026
Identifier
1K99HL183664-01A1
NIH awarded a grant to develop nanoparticle therapy targeting endothelial epsins to improve stroke recovery, led by Dr. Kulandaisamy Arulsamy at Boston Children's Hospital, with an award amount of $139,822.
Description
This NIH-funded project aims to uncover the role of endothelial epsins in regulating CXCR4-mediated angiocrine signaling and develop targeted nanoparticle therapy to enhance vascular regeneration after stroke. The project focuses on developing nanoparticle therapy targeting endothelial epsins to improve stroke recovery. The project is led by Dr. Kulandaisamy Arulsamy, a Research Fellow. The award is part of NIH's PA-24-194 funding opportunity. The project duration is from July 21, 2026, to May 31, 2028. The project aims to establish a new therapeutic paradigm for ischemic stroke and cardiovascular diseases.