Award
Florida Department of Veterans' Affairs 5I01BX004626-06
Controlling FKBP51 for the treatment of PTSD
Recipient
James A. Haley VA Medical Center
Awarded
October 06, 2025
Identifier
5I01BX004626-06
This award supports research to develop antisense oligonucleotides targeting FKBP51 to treat PTSD in veterans, validating FKBP51 as a therapeutic target using mouse models.
Description
The project aims to develop novel therapeutic strategies to deplete FKBP51 using antisense oligonucleotides and to validate FKBP51 as a target for regulating resilience in PTSD using mouse models. It focuses on PTSD and neuropsychiatric disorders in veterans, particularly related to the FKBP5 gene and its protein FKBP51.