Award

NIH Reporter #5R01MH128286-05

Individualized brain biomarkers of late life depression: contributions to heterogeneity and resilience

Recipient

Washington University, Saint Louis, MO, United States

Award Amount

$464,438.00

Ceiling

$464,438.00

Awarded

May 20, 2026

Identifier

5R01MH128286-05

The project studies brain measures in older adults to understand heterogeneity in late-life depression and the impact of stressors on resilience and vulnerability, aiming to improve treatment and prevention.

Description

This project aims to distinguish brain profiles linked to differences in depression symptoms, severity, age of first depression, and number of episodes. It will also identify environmental and psychological stress factors influencing vulnerability or resilience to depression.

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