Award
National Institute of General Medical Sciences 5R35GM146859-06
Endothelial regulation of inflammation in trauma and hemorrhagic shock
Recipient
University of Colorado Denver, Aurora, CO
Award Amount
$390,000.00
Ceiling
$390,000.00
Awarded
May 11, 2026
Identifier
5R35GM146859-06
A multi-year NIH research project investigating the vascular endothelium's role in inflammation and organ injury after trauma, aiming to develop new therapeutic interventions.
Description
This project aims to examine key contributions of the vascular endothelium to immunomodulation after traumatic injury, focusing on mechanisms that regulate inflammation and organ injury. The research will explore the immunomodulatory functions of the antithrombin-heparan sulfate system, aiming to develop novel therapeutics to mitigate inflammation and organ failure in trauma patients.