Award
National Institute on Drug Abuse 5R01DA062186-02
Optimizing methadone treatment strategies for opioid use disorder in the era of fentanyl
Recipient
Brown University, Providence, RI, United States
Award Amount
$855,061.00
Ceiling
$855,061.00
Awarded
May 19, 2026
Identifier
5R01DA062186-02
The award supports a study to optimize methadone treatment strategies for opioid use disorder amid fentanyl prevalence, focusing on dosing and take-home policies to improve retention and reduce overdose risk using linked health data in Rhode Island.
Description
This project aims to evaluate the effectiveness and safety of different methadone treatment strategies, including dosing and expanded take-home flexibilities, on treatment retention and overdose outcomes in patients with opioid use disorder during the fentanyl era. The study will leverage a comprehensive dataset combining electronic health records and state administrative data in Rhode Island.