Award
California Department of Veterans Affairs BX-24-044
Validation of a novel drug target to treat RV failure
Recipient
VETERANS AFFAIRS MED CTR SAN FRANCISCO
Awarded
October 03, 2025
Identifier
BX-24-044
Award for developing and testing novel α1A-AR agonists to treat right ventricular failure, funded by Veterans Affairs.
Description
This project aims to develop and test proprietary α1A-AR agonists to treat right ventricular failure, with a focus on creating clinically viable drugs with IP value. The project includes developing 30 proprietary agonists, screening for signaling mediation, and testing the best candidate in vivo for RVF reversal. The project is funded by the VA and is part of the Merit Review Pilot Project Awards to Validate Clinically Significant Novel Therapeutic Target(s).