# NIH Reporter #4R37CA262635-06

Dissecting the Role Ubiquitin E3 Ligase UBR5 in Lymphomagenesis

**Recipient:** Utah State Higher Education System—University of Utah

**Award Amount:** $410,861.00
**Ceiling:** $410,861.00

**Awarded:** August 26, 2026

**Identifier:** 4R37CA262635-06

The project studies how UBR5, particularly its HECT and MLLE domains, contributes to B-cell maturation and mantle cell lymphoma progression, with the aim of informing future therapeutic targets.

### Description

Project investigating UBR5 mutations and their role in B-cell development, mantle cell lymphoma progression, and lymphomagenesis.

[View original record](https://reporter.nih.gov/search/7U_RDKopbE--cH-2OrGcnA/project-details/11293301)