Award
National Institute of Neurological Disorders and Stroke 5R37NS061817-16
Oxidative Lipidomics in Pediatric Traumatic Brain Injury
Recipient
Columbia University Health Sciences
Award Amount
$397,501.00
Ceiling
$397,501.00
Awarded
May 01, 2026
Identifier
5R37NS061817-16
The project focuses on understanding oxidative stress and lipid peroxidation mechanisms in pediatric TBI to develop targeted therapies that prevent neuronal death and improve neurological outcomes in children.
Description
This project will identify the role of oxidized phospholipids in neuronal death after pediatric traumatic brain injury (TBI) using state-of-the-art oxidative lipidomics. The research aims to test novel therapeutic compounds to prevent neuronal death and improve outcomes in pediatric TBI, potentially leading to targeted therapies.