Award
National Institute of Arthritis and Musculoskeletal and Skin Diseases 5R01AR070613-09
Raman spectroscopic platform for transcutaneous monitoring of bone quality
Recipient
University of Rochester, Rochester, NY, United States
Award Amount
$488,612.00
Ceiling
$488,612.00
Awarded
April 28, 2026
Identifier
5R01AR070613-09
This NIH grant supports the development of a Raman spectroscopy platform for noninvasive monitoring of bone quality to improve osteoporosis screening and fracture risk assessment.
Description
Development of a noninvasive optical vibrational spectroscopy tool to assess bone quality and fracture risk, addressing challenges in soft tissue interference, correlation with clinical BMD scores, and safety in humans. The project includes spectral algorithm adaptation, correlation studies, and pilot human studies to demonstrate proof-of-concept for clinical use.