Award
NIH Reporter #5K25CA297149-02
Resolving phenotypic overlap in renal carcinoma subtypes using multi-tiered network methods
Recipient
Dana-Farber Cancer Institute
Award Amount
$167,543.00
Ceiling
$167,543.00
Awarded
April 03, 2026
Identifier
5K25CA297149-02
Award for research on renal carcinoma subtypes using computational methods to improve diagnosis and treatment, funded by the National Cancer Institute and conducted at Dana-Farber Cancer Institute.
Description
The project focuses on genetic and molecular analysis of renal carcinoma subtypes. It involves developing computational methods for gene regulatory and metabolic network analysis. The research is supported by NIH and conducted at Dana-Farber Cancer Institute. The goals are to characterize subtype-specific gene regulatory elements in translocation renal cell carcinoma (tRCC) by identifying differentially active transcription factors, determining their metabolic functions, and genetic variants controlling their activity to improve diagnosis, molecular definition, and response prediction for tRCC.