Award
National Institute on Aging 2R56AG066184-06A1
Dissecting the Neural Circuitry Linking GLP-1 Receptor Agonists to Cardiovascular Health
Recipient
National Institute on Aging (NIA), part of the NIH, United States
Award Amount
$399,047.00
Ceiling
$399,047.00
Awarded
June 25, 2026
Identifier
2R56AG066184-06A1
Research project studying the protective effects of GLP-1 receptor agonists and exercise on brain and heart health in mouse models of Alzheimer's and cardiovascular disease using advanced techniques.
Description
This project investigates how GLP-1 receptor agonists, alone and combined with exercise, protect the brain and heart in mouse models representing genetic risk for Alzheimer's disease and cardiovascular disease. It involves advanced imaging, molecular profiling, and machine learning to uncover shared neurocardiac pathways and inform targeted prevention strategies.