Award
National Institute of Arthritis and Musculoskeletal and Skin Diseases 5R01AR077563-05
Molecular Determinants of Pigmentation (MDoP)
Recipient
University of Maryland Baltimore
Award Amount
$459,630.00
Ceiling
$459,630.00
Awarded
February 26, 2026
Identifier
5R01AR077563-05
NIH grant awarded to University of Maryland Baltimore to study genetic and molecular bases of pigmentation disorders, aiming to identify novel genes and develop therapies.
Description
The "Molecular Determinants of Pigmentation (MDoP)" study aims to identify and characterize new genes and proteins essential for pigmentation development, melanosomes transportation, function, and maintenance in humans. The study focuses on pigmentation disorders such as albinism, including syndromic and nonsyndromic forms, with the goal to understand mechanisms and develop therapeutic agents. The research uses genetic, molecular, biochemical, psychophysical, and cell biology techniques in humans and zebrafish models.