Award
NIH Reporter #1R01HD120348-01
Effects of the ovarian mechanical properties on folliculogenesis
Recipient
Washington University, Saint Louis, MO
Award Amount
$461,435.00
Ceiling
$461,435.00
Awarded
May 07, 2026
Identifier
1R01HD120348-01
NIH funded project studying the impact of ovarian stiffness on follicle inflammation and reproductive aging, aiming to understand mechanisms impairing fertility and ovarian function.
Description
This NIH research project focuses on the effects of ovarian mechanical properties on folliculogenesis, investigating how increased ovarian stiffness with age affects follicle inflammation, oocyte quality, ovarian function, and fertility. The study aims to define the contribution of microenvironment stiffness to follicle inflammation, determine effects of mechanical inputs on follicle function, and assess ovarian stiffness impact on oocyte quality and fertility.