Award
NIH Reporter #5F31HG013609-03
Robust and scalable Bayesian analysis tools for single cell CRISPR screens with sequencing- and imaging-based readouts
Recipient
Harvard Medical School, Boston, MA, United States
Award Amount
$34,114.00
Ceiling
$34,114.00
Awarded
July 29, 2026
Identifier
5F31HG013609-03
Development of Bayesian analysis tools for single-cell CRISPR screens to identify biological pathways related to blood and neurodegenerative diseases.
Description
This project aims to develop computational tools based on Bayesian hierarchical models to analyze large and complex datasets generated by single-cell CRISPR screens. The tools will help identify core biological pathways underlying blood and neurodegenerative diseases, facilitating therapeutic target nomination and advancing understanding of biological pathways and gene regulatory networks.