Award
National Institute on Aging 5R01AG068261-03
Connectomic Biomarkers of Preclinical Alzheimer's Disease within Multi-Synaptic Pathways
Recipient
Massachusetts General Hospital
Award Amount
$584,403.00
Ceiling
$584,403.00
Awarded
April 13, 2026
Identifier
5R01AG068261-03
Award for research on developing models for brain connectivity to improve understanding and prediction of Alzheimer's Disease using data from multiple databases.
Description
This project involves developing and validating mathematical and algorithmic models for brain connectivity, focusing on multi-synaptic neural pathways, and including a comprehensive set of brain regions, especially those important in Alzheimer's Disease. The study will analyze data from approximately 6000 subjects across multiple databases to improve stratification, prediction, and prognosis of Alzheimer's Disease.