Award
National Institute of General Medical Sciences 5R35GM145257-04
Translation regulation by molecular switch RNA-binding protein LARP1
Recipient
University of Pittsburgh at Pittsburgh, PA, USA
Award Amount
$385,431.00
Ceiling
$385,431.00
Awarded
July 16, 2025
Identifier
5R35GM145257-04
NIH research grant awarded to University of Pittsburgh to study translation regulation by RNA-binding protein LARP1, aiming to understand molecular mechanisms of gene expression control through translation.
Description
Research program to uncover molecular mechanisms underlying RNA-binding protein regulation of translation, focusing on LARP1 as a model system to understand how cells integrate information from multi-RBD RBPs, post-translational modifications, and post-transcriptional mRNA modifications to direct translation of specific transcripts.