Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK078184-17
Factors Controlling Metabolic Flux in the Liver
Recipient
UT Southwestern Medical Center, Dallas, TX
Award Amount
$508,728.00
Ceiling
$508,728.00
Awarded
February 24, 2026
Identifier
5R01DK078184-17
The award supports research on mitochondrial metabolism's role in non-alcoholic fatty liver disease, specifically how anaplerotic pathways affect liver mitochondrial function and antioxidant capacity.
Description
This project investigates how anaplerosis impacts mitochondrial metabolism and impinges on liver disease, focusing on mitochondrial function, redox state, and antioxidant capacity in the context of obesity related liver disease.