# NIH Reporter #4K00CA294251-03

Intercellular Communication in Cancer Cachexia: Impact of Obesity and Exercise

**Recipient:** Colorado State University

**Award Amount:** $99,216.00
**Ceiling:** $99,216.00

**Awarded:** January 27, 2026

**Identifier:** 4K00CA294251-03

The project investigates extracellular vesicles as mechanisms linking cancer, obesity, and skeletal muscle dysfunction, and explores whether exercise can improve muscle health and quality of life in cancer survivors.

### Description

Research project examining how extracellular-vesicle communication among tumors, adipose tissue, and skeletal muscle contributes to cancer cachexia with obesity, and whether exercise can modulate EV signaling to improve skeletal muscle health.

[View original record](https://reporter.nih.gov/search/7U_RDKopbE--cH-2OrGcnA/project-details/11457170)