National Institute of Allergy and Infectious Diseases 5K08AI171166-04

Mechanistic characterization of vaginal microbiome-metabolome associations and metabolite-mediated host inflammation

NIH awarded a research grant to Massachusetts General Hospital to study vaginal microbiome metabolites and their role in inflammation, aiming to develop new therapies for vaginal diseases.

Description

This NIH research grant focuses on studying how metabolites in vaginal fluid produced by the microbiome influence host inflammation and aims to identify new therapies for vaginal diseases. The project includes characterizing metabolome and metagenome in cohorts, studying enzymes in vaginal bacteria, and assessing effects on host responses.

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