Award

National Heart, Lung, and Blood Institute 5R33HL161752-05

Leveraging behavioral economics to implement cascade screening in individuals with familial hypercholesterolemia

Recipient

Northwestern University, Chicago, IL

Award Amount

$515,597.00

Ceiling

$515,597.00

Awarded

April 27, 2026

Identifier

5R33HL161752-05

This NIH-funded project tests behavioral economics-informed strategies to improve cascade screening for familial hypercholesterolemia, aiming to increase diagnosis and reduce morbidity through a randomized controlled trial.

Description

The project leverages a partnership with the Family Heart Foundation to refine and test two approaches to implement cascade screening in individuals with familial hypercholesterolemia (FH). The study aims to improve timely FH diagnosis and reduce morbidity by testing health system-mediated and Family Heart Foundation-mediated strategies informed by behavioral economics in a randomized controlled trial with 300 probands from Penn Medicine.

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