Award
National Institute of Neurological Disorders and Stroke 5R01NS129992-04
Genetic Analyses of Dendrite Morphogenesis in Caenorhabditis Elegans
Recipient
Albert Einstein College of Medicine, Bronx, NY, United States
Award Amount
$411,224.00
Ceiling
$411,224.00
Awarded
June 11, 2026
Identifier
5R01NS129992-04
Research project funded by the National Institute of Neurological Disorders and Stroke to study genetic and molecular mechanisms regulating dendrite branching in C. elegans, with implications for neurodevelopmental disorders.
Description
This project investigates genetic and molecular mechanisms of dendrite development in C. elegans, focusing on genes that restrict branching and the control of dendritic field size. It aims to uncover mechanisms of dendrite development relevant to neuropathological conditions such as mental retardation and autism spectrum disorders, using molecular, genetic, imaging, and biochemical approaches.