Award
National Institute of General Medical Sciences 1R35GM161407-01
The Functional, Phenotypic, and Evolutionary Significance of Human Genomic Variation
Recipient
Princeton University
Award Amount
$451,000.00
Ceiling
$451,000.00
Awarded
August 04, 2026
Identifier
1R35GM161407-01
This award funds research to develop new methods for genome assembly and population genetics, focusing on human genomic variation, archaic hominin admixture, and somatic mutations to advance understanding of human genome biology and evolution.
Description
The project aims to better understand the functional, phenotypic, and evolutionary consequences of germline and somatic variation in humans. It involves developing novel methods to improve genome assembly and population genetics inferences, constructing high-quality genomes from understudied populations, and studying archaic hominin admixture and somatic mutations. The research will provide insights into human genome biology, evolution, and diversity.