National Institute of Environmental Health Sciences 5P30ES005022-39

Human/Animal Exposure

The HUMANE Facility Core at Rutgers Biomedical and Health Sciences is funded to provide advanced tools and platforms for studying environmental exposures and their health impacts on humans and animals, supporting interdisciplinary research and enhancing capabilities for future studies.

Description

The Human and Animal Exposure (HUMANE) Facility Core provides tools to address environmental health concerns of NJ residents. It collaborates with researchers to design experiments assessing how real-world exposures affect biological responses linked to health outcomes in humans and animals. The core utilizes advanced exposure platforms for generating and measuring environmental toxicants, including nanoparticles from sources like wildfires, micro-nanoplastics, e-cigarettes, and engineered nanomaterials. It supports inhalation studies examining interactions with variables such as temperature, humidity, physical activity, and stress. The core enhances its capabilities with new platforms and equipment, facilitating bidirectional translation of research findings to understand disease mechanisms and intervention strategies. It collaborates with other cores to ensure high standards of safety and quality. Planned investments aim to increase utilization and enable studies on airborne infection transmission.

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