Award
National Institute on Aging 5R01AG082800-04
Harnessing CAR T cells to deconstruct the interconnectivity among hallmarks of aging
Recipient
Corina Amor Vegas
Award Amount
$516,478.00
Ceiling
$516,478.00
Awarded
September 15, 2023
Identifier
5R01AG082800-04
This award funds research to develop and use CAR T cell therapy to investigate and target aging hallmarks, with promising preliminary results in aged mice.
Description
The project involves developing and utilizing cellular therapy, specifically CAR T cells, to study aging hallmarks. The project aims to develop tissue-specific senolytic CAR T cells and study their therapeutic potential. Preliminary data shows successful and safe employment of senolytic CAR T cells in aged mice.