Award

National Institute of Mental Health 5R01MH128155-05

Novel macrophage-tropic transmitted/founder SHIV model of CNS persistence to evaluate CRISPR/Cas9 gene editing

Recipient

University of Pennsylvania, Philadelphia

Award Amount

$696,272.00

Ceiling

$696,272.00

Awarded

April 25, 2025

Identifier

5R01MH128155-05

Award for developing a macrophage-tropic SHIV model to study CNS persistence and evaluate CRISPR/Cas9 gene editing, funded by NIH/NIMH with $696,272.

Description

This project involves the development of a macrophage-tropic SHIV model for CNS persistence and testing CRISPR/Cas9 gene editing strategies. The funding agency is the NIH/NIMH, with a total award amount of approximately $696,272. The project aims to improve understanding of HIV reservoirs in the brain and develop potential cure strategies.

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