Award
National Cancer Institute 1R01CA315861-01
Individualized DNA junctions for glioma response assessment via longitudinal liquid biopsies
Recipient
National Cancer Institute (NCI)
Awarded
July 24, 2026
Identifier
1R01CA315861-01
Award for research project to develop DNA junction assays in cerebrospinal fluid for monitoring glioma through longitudinal liquid biopsies, including applications in CAR-T therapy.
Description
This project aims to establish and validate DNA junction assays in cerebrospinal fluid samples as biomarkers for glioma monitoring, leveraging patient-specific genomics and ongoing clinical trials. The work involves longitudinal liquid biopsies, comparison of plasma and CSF, and application in CAR-T therapy monitoring.