Eunice Kennedy Shriver National Institute of Child Health and Human Development 1R03HD111008-01A1

Validating non-linguistic laboratory biomarkers of depression in persons with aphasia

NIH-funded project to validate non-linguistic laboratory biomarkers for detecting depression in persons with aphasia using multi-modal assessments.

Description

This project focuses on using multi-modal assessments (eye-tracking, pupil dilation, resting-state heart rate variability) to identify depression in persons with aphasia. It aims to validate laboratory biomarkers that require minimal language abilities and can robustly identify depression, which is challenging due to language disturbances in this population. The study involves a composite reference standard for depression, experience sampling methodology, and test-retest reliability assessments.

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