Award
University of Virginia 11350985
Endothelial Cell Cycle Control to Normalize the Tumor Vasculature
Recipient
University of Virginia
Awarded
June 10, 2026
Identifier
11350985
Research project focused on normalizing tumor vasculature by controlling endothelial cell cycle using Palbociclib in mouse models to improve drug delivery and vessel function.
Description
This project involves research on tumor vasculature normalization using cell cycle inhibitors, specifically Palbociclib, in mouse models. The study aims to quantify endothelial cell cycle states, vessel permeability, and drug delivery efficacy.