Award
NIH Reporter #1ZIAAG000946-18
Pathogenic Mechanisms of ALS and Motor Neuron Diseases
Recipient
Not Specified
Award Amount
$25,007.00
Ceiling
$25,007.00
Awarded
October 01, 2023
Identifier
1ZIAAG000946-18
Research project studying the molecular and cellular mechanisms by which the VAPB P56S mutation leads to selective corticospinal motor neuron degeneration in ALS, using a knock-in mouse model to identify key signaling pathways and potential therapeutic targets.
Description
This project investigates the molecular mechanisms underlying ALS, focusing on the VAPB P56S mutation using a mouse model. It aims to identify pathways involved in motor neuron degeneration and potential therapeutic targets.