Award
NIH Reporter #5R01CA304244-02
Development of nanoscale infrared spectroscopic imaging for measuring cellular ultrastructure
Recipient
University of Illinois at Urbana-Champaign
Award Amount
$509,352.00
Ceiling
$509,352.00
Awarded
August 24, 2026
Identifier
5R01CA304244-02
Award to University of Illinois at Urbana-Champaign to develop advanced AFM-IR imaging technology for nanoscale chemical imaging of biological samples, improving resolution, sensitivity, and speed.
Description
This project aims to develop a new AFM-IR technology, dubbed resonance-enhanced null-deflection IR (RENDIR) spectroscopic imaging, which will include custom electronics, optimized data recording, expanded laser range, and novel optics. These advances will enable high-quality signals, ~5 nm resolution, lower noise, higher sensitivity, and faster data acquisition, surpassing current state-of-the-art techniques.