Award
National Eye Institute 1R01EY038520-01
Mechanobiology of Bruch’s membrane during aging: Implications for age-related retinal degenerations.
Recipient
BELA ANAND-APTE
Award Amount
$615,928.00
Ceiling
$615,928.00
Awarded
April 15, 2026
Identifier
1R01EY038520-01
This NIH-funded project by the National Eye Institute studies the aging effects on Bruch’s membrane and its role in retinal degenerations, with an award amount of approximately $615,928 for fiscal year 2026.
Description
The project focuses on the mechanobiology of Bruch’s membrane during aging and its implications for age-related retinal degenerations. It involves studying the spatial and temporal matrisome maps of RPE/Bruch’s membrane/choriocapillaris and correlating it with tissue stiffness to identify changes with aging and provide mechanistic insights into how stiffness affects RPE barrier function and metabolism.