Award
National Institute of Diabetes and Digestive and Kidney Diseases 5F30DK138638-02
Mechanisms of osmosensing in GI enteroendocrine cells
Recipient
Mayo Clinic Rochester
Award Amount
$49,738.00
Ceiling
$49,738.00
Awarded
August 19, 2025
Identifier
5F30DK138638-02
Research project funded to investigate cellular pathways by which EECs transduce osmotic stimuli and their effects on GI motility, relevant to treating disorders like IBS.
Description
This project aims to uncover how enteroendocrine cells (EECs) sense osmotic stimuli and how this influences signal molecule release and gastrointestinal motility, potentially identifying new targets for disorders of gut-brain interaction treatment.