# NIH Reporter #5R01AR083960-02

T-cell plasticity mediating treatment resistance and side effects in atopic dermatitis

**Recipient:** Icahn School of Medicine at Mount Sinai

**Award Amount:** $500,516.00
**Ceiling:** $500,516.00

**Awarded:** August 07, 2026

**Identifier:** 5R01AR083960-02

The project investigates T-cell plasticity and immune mechanisms associated with dupilumab treatment resistance and paradoxical inflammatory skin effects in atopic dermatitis, with the goal of informing improved therapies.

### Description

Research project studying immune mechanisms underlying treatment-resistant atopic dermatitis and inflammatory side effects in patients treated with dupilumab.

[View original record](https://reporter.nih.gov/search/7U_RDKopbE--cH-2OrGcnA/project-details/11389364)