Award
National Institute of Mental Health 5R01MH137305-03
Microglial-serotonin interactions in the developing brain.
Recipient
Duke University, Durham, NC
Award Amount
$479,118.00
Ceiling
$479,118.00
Awarded
February 23, 2026
Identifier
5R01MH137305-03
Research project funded by the National Institute of Mental Health to study how microglia interact with serotonin neurons during brain development, particularly in the context of maternal high fat diet effects on neurodevelopment and behavior.
Description
This project investigates the role of microglia in serotonin system disruptions related to maternal diet and neurodevelopmental outcomes. It aims to elucidate mechanisms by which microglia target serotonin cells and how maternal diet influences neural circuits underlying behavioral differences, with implications for mental health disorders such as depression and social communication difficulties.