Award
National Institute of Allergy and Infectious Diseases 5R01AI175177-03
C. albicans-intrinsic mechanisms defining gut colonization
Recipient
Brown University, Providence, RI
Award Amount
$456,224.00
Ceiling
$456,224.00
Awarded
May 27, 2026
Identifier
5R01AI175177-03
Research project funded by NIAID to study Candida albicans gut colonization mechanisms, including toxin role and microbial interactions, using murine models.
Description
The project aims to investigate the mechanisms by which Candida albicans colonizes the gastrointestinal (GI) tract, focusing on the role of Candidalysin toxin in fungal fitness and competition with bacterial microbiota. The research will utilize murine models to study morphology, gene regulation, and interkingdom interactions affecting gut colonization.