Award
National Cancer Institute RFA-CA-25-002
Advancing and Validating Single-Cell Long-Read Sequencing for Broad Adoption in Cancer Molecular Profiling
Recipient
Jackson Laboratory
Award Amount
$452,458.00
Ceiling
$452,458.00
Awarded
July 16, 2026
Identifier
RFA-CA-25-002
NIH awarded a research grant to advance and validate single-cell long-read sequencing techniques for cancer molecular profiling, focusing on tumor heterogeneity and splicing analysis using in vivo models.
Description
A research grant opportunity from the NIH for advancing single-cell long-read sequencing in cancer research. The project aims to develop and validate new tools and methods, including bioinformatics pipelines, for analyzing tumor heterogeneity and splicing at the single-cell level. It involves in vivo models, including patient-derived xenografts and tumor types such as breast, lung, and nerve tumors, with an emphasis on open data sharing and visualization tools.