Award

National Institute on Drug Abuse 7R01DA054101-05

Evaluating a Mechanistically-Supported Pharmacotherapy to Treat Acute and Protracted Opioid Withdrawal

Recipient

University of Maryland Baltimore, Baltimore, MD

Award Amount

$730,696.00

Ceiling

$730,696.00

Awarded

May 01, 2026

Identifier

7R01DA054101-05

This award funds a clinical trial to test buspirone's effectiveness in treating opioid withdrawal and reducing relapse in opioid use disorder patients through a residential and outpatient treatment protocol.

Description

A Phase II, three-group, placebo-controlled double-blind RCT to evaluate the efficacy of buspirone for acute and protracted opioid withdrawal as an adjunctive pharmacotherapy to a residential opioid stepwise taper and outpatient phase.

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