Award
NIH Reporter #2R15HL129209-04
Experimental and Computational Investigation of NOX4-Dependent Mechanisms in ARDS Susceptibility
Recipient
Marquette University
Award Amount
$557,963.00
Ceiling
$557,963.00
Awarded
August 04, 2026
Identifier
2R15HL129209-04
Research grant awarded to Marquette University to investigate NOX4's role in ARDS susceptibility, aiming to identify therapeutic targets and provide research training.
Description
This project will define how the oxidant-producing enzyme NOX4 regulates susceptibility to ARDS caused by hyperoxia or sepsis. The findings will reveal new mechanisms and therapeutic targets to reduce ARDS mortality while providing immersive research training for undergraduate and graduate students in physiology, bioengineering, and computational modeling.