Award
National Institute of Dental and Craniofacial Research 5R01DE008007-36
MEMBRANES OF THE DENTAL PATHOGEN STREPTOCOCCUS MUTANS
Recipient
University of Florida, Gainesville, FL
Award Amount
$511,145.00
Ceiling
$511,145.00
Awarded
July 01, 2026
Identifier
5R01DE008007-36
Award for research on membrane protein insertion in Streptococcus mutans to understand how disease-related proteins are transported into bacterial membranes, facilitating targeted therapy against dental pathogens.
Description
This research explains how proteins important for disease get into the membrane of Streptococcus mutans and other related pathogens. The project addresses membrane protein insertion in S. mutans, a major global infectious agent causing dental caries and other diseases. It studies co-translational protein transport, signal recognition particle pathway, protein interactions, and roles of specific proteins in regulation using advanced molecular techniques.