Award
National Institute of Environmental Health Sciences 5U01ES033263-05
Novel lead compound advancement for mitigating halogen-induced mortality and morbidity.
Recipient
National Institute of Environmental Health Sciences (NIEHS)
Award Amount
$693,017.00
Ceiling
$693,017.00
Awarded
June 25, 2026
Identifier
5U01ES033263-05
Award for research on calpain inhibitors to treat halogen gas-induced cardiopulmonary injuries, including molecular validation, efficacy studies, and regulatory support.
Description
The project focuses on developing and optimizing calpain inhibitors for therapeutic use against halogen gas-induced cardiopulmonary injuries. The project includes validation of molecular targets, in vitro activity testing, in vivo efficacy studies, and ADME/Tox evaluations. The project aims to support regulatory approval under the animal rule.