Award
National Institute of Environmental Health Sciences 5R00ES034507-04
Respiratory Effects, Metal and Aldehyde exposure from e-cigarette use in young adults (REMA)
Recipient
University of Pennsylvania, Philadelphia, PA
Award Amount
$249,000.00
Ceiling
$249,000.00
Awarded
September 12, 2025
Identifier
5R00ES034507-04
A research project funded by NIEHS to study the respiratory health effects and chemical exposures from e-cigarette use in young adults, aiming to inform FDA regulations.
Description
Investigate the exposure and toxicity of chemical constituents of concern (metals and aldehydes) and pulmonary health effects including inflammation from new and emerging electronic cigarette devices among young adults. The study will recruit participants to assess biomarkers of exposure and effect, analyze respiratory outcomes, and use Bayesian and causal mediation methods to understand if exposure mediates respiratory effects. The goal is to generate data to inform FDA regulation to limit adverse exposures and health outcomes.