Award
National Institute of Allergy and Infectious Diseases 5R01AI182148-02
iPSC-derived macrophages as a model to study the genetic basis of inter-individual variation in immune responses to pathogens
Recipient
University of Chicago
Award Amount
$809,805.00
Ceiling
$809,805.00
Awarded
January 06, 2026
Identifier
5R01AI182148-02
This NIH-funded project uses iPSC-derived macrophages to investigate genetic and epigenetic factors affecting immune response variability to pathogens, with a total award amount of approximately $809,805 for FY 2026 and a project duration from January 24, 2025, to December 31, 2029.
Description
The project aims to use induced pluripotent stem cell-derived macrophages to study genetic and epigenetic factors influencing immune response variability to infectious agents such as Mtb and influenza. The project involves advanced genomics, computational biology, and immunology techniques.