Award
National Institute of Neurological Disorders and Stroke 5SC1NS127764-04
APE1 and Somatic Expansion in Huntington's Disease
Recipient
National Institute of Neurological Disorders and Stroke (NINDS), NIH, US
Award Amount
$327,094.00
Ceiling
$327,094.00
Awarded
March 21, 2025
Identifier
5SC1NS127764-04
Research award to study the role of APE1 in Huntington's Disease and its impact on somatic expansion and age of onset, aiming to develop therapeutics for neurodegenerative diseases.
Description
The project focuses on the role of APE1 in Huntington's Disease, specifically its impact on somatic expansion and age of onset. The research aims to elucidate the mechanistic functions of APE1 and mutant HTT. The award is part of NIH's efforts to develop therapeutics for neurodegenerative diseases.