Award
National Institute of Neurological Disorders and Stroke 1K23NS144635-01
Neuroimaging biomarkers for sense of control, catastrophic expectations, and stress reactivity as novel treatment targets for functional seizures.
Recipient
University of Alabama at Birmingham
Award Amount
$175,530.00
Ceiling
$175,530.00
Awarded
August 01, 2025
Identifier
1K23NS144635-01
This award funds a study to develop neuroimaging biomarkers for functional seizures by analyzing brain activity related to emotion and stress, aiming to improve understanding and treatment of the disorder.
Description
The proposed study aims to develop neuroimaging-based outcome measures for functional seizures by examining neural activity in brain regions associated with emotion processing and control. The study involves 40 adults with functional seizures and 40 matched controls undergoing fMRI while completing tasks assessing neural responses to threats and stress. The goal is to uncover neural substrates of abnormal behavior in functional seizures, enhance understanding of their pathophysiology, and improve interventions.