Award
National Institute of Allergy and Infectious Diseases 5P01AI150585-05
Molecular Mechanisms of the Dysregulated Immune Response to Ebola Virus
Recipient
University of Texas Medical Branch at Galveston, Galveston, TX, United States
Award Amount
$2,295,613.00
Ceiling
$2,295,613.00
Awarded
April 16, 2025
Identifier
5P01AI150585-05
A federal research grant awarded to study the molecular mechanisms of immune response dysregulation in Ebola virus disease, involving advanced molecular and immunological analyses.
Description
This project aims to elucidate the molecular mechanisms underlying the dysregulated immune response in Ebola virus disease (EVD). It involves comprehensive analysis of transcriptional, posttranscriptional, and posttranslational alterations in immune cells caused by Ebola virus infection. The study will utilize BSL-4 facilities for infection experiments, and will include mass spectrometry, sequencing, and bioinformatics modeling to develop a detailed understanding of immune dysregulation.