Award
NIH Reporter #5R01EB032324-04
AC-225 Imaging R01 Transfer
Recipient
Not specified
Award Amount
$1,070,638.00
Ceiling
$1,070,638.00
Awarded
July 11, 2025
Identifier
5R01EB032324-04
Award for developing a gamma imaging device combining Compton and proximity reconstructions to image 225Ac biodistributions for targeted alpha therapy research.
Description
The project aims to develop a novel gamma imaging device based on the combination of Compton and proximity reconstructions to enable in vivo imaging of biodistributions of 225Ac, a promising Targeted Alpha Therapy (TAT) isotope. The system will utilize a Cadmium Zinc Telluride dual-head camera to perform both imaging techniques, facilitating the study of pharmacokinetics of radiopharmaceuticals in pre-clinical models.