Award
NIH Reporter #5P01CA291694-02
Epigenomics of Mutant p53
Recipient
Icahn School of Medicine at Mount Sinai, New York, NY, USA
Award Amount
$307,680.00
Ceiling
$307,680.00
Awarded
August 25, 2026
Identifier
5P01CA291694-02
This NIH grant supports research on the epigenomics of mutant p53, providing advanced sequencing and bioinformatics to understand mutant p53's role in cancer biology.
Description
NIH-funded research project focusing on epigenomic and transcriptomic analysis of mutant p53 in cancer biology. The project involves advanced sequencing techniques, bioinformatics, and data integration platforms. Core 1 provides transcriptomic and epigenomic experimental approaches, next-generation sequencing expertise, computational analysis, and bioinformatic tools for data visualization and integration of large 'omic datasets. It aims to establish a reference epigenome, generate chromatin states and complete transcriptomes, and develop novel hypotheses to understand mutant p53 enrichment patterns genome-wide.