Award
NIH Reporter #5R01HD115879-02
The promotion of parental behavior by the neurosteroid allopregnanediol
Recipient
Not Specified
Award Amount
$589,672.00
Ceiling
$589,672.00
Awarded
October 04, 2023
Identifier
5R01HD115879-02
Research project funded by NICHD to study how the neurosteroid Allodiol promotes parental behavior in mice, with implications for understanding postpartum depression and child neglect in humans.
Description
This project aims to characterize the mechanisms of action of the neurosteroid Allodiol, which promotes parental behavior in mice and is nearly identical to allopregnanolone, the only drug approved to treat postpartum depression in humans. The study uses Peromyscus mice to investigate hormonal modulation of parental care, focusing on the neurosteroid's effects in the brain to modulate parental care.